The tools provided here may be useful to you throughout your treatment with SAPHRIS sublingual tablets.
Tools you can print and use
Download and print helpful tools you can use during your treatment with SAPHRIS.
Watch the video
SAPHRIS is a type of medicine called an atypical antipsychotic
. It is approved for the acute treatment of manic or mixed episodes associated with bipolar I
disorder in adults.
It may be taken alone or with a mood stabilizer (lithium or valproate).
Important Safety Information
Tardive dyskinesia (TD):
Tell your healthcare provider if you experience uncontrollable movements of the face, tongue, or other parts of the body. These could be signs of a serious and sometimes permanent side effect (TD). The risk for developing TD and the chance that it will become permanent is thought to increase the longer a person takes the medicine and the more medicine a person takes over time. TD can develop after a person has been taking the medicine for a short time at low doses, although this is much less common. There is no known treatment for TD, but it may go away partially or completely if the person stops taking the medicine.
High blood sugar:
If you have diabetes or risk factors for diabetes, such as being overweight or a family history of diabetes, your blood sugar should be tested at the beginning of and throughout treatment with SAPHRIS. Complications of diabetes can be serious and even life threatening. Tell your healthcare provider if you have blood sugar problems or signs of diabetes, such as being thirsty all the time, going to the bathroom a lot, or feeling weak or hungry.
Some patients may gain weight while taking SAPHRIS. Your healthcare provider should check your weight regularly.
Other important information to remember:
- Get up slowly after sitting or lying down to avoid getting dizzy, especially at the start of treatment, or when your dose is increased. Light-headedness or faintness caused by a sudden change in heart rate and blood pressure when rising quickly from a sitting position has been reported with SAPHRIS
- Do NOT drive or use dangerous machines until you know how SAPHRIS affects you, because SAPHRIS and medicines like it can affect your judgment, thinking, and motor skills
- Be careful when exercising or when doing things likely to cause dehydration or make you warm, because SAPHRIS may make you more sensitive to heat. You may have trouble cooling off
- Do NOT drink alcohol
- Breastfeeding is NOT recommended
- The most common side effects that occurred with SAPHRIS were sleepiness, dizziness, uncontrolled movements of the body and face, muscle stiffness, weight gain, numbing of the mouth, and restlessness
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call
Please click here for Prescribing Information, including the Boxed
Warning about increased risk of death in elderly people with dementia-related psychosis (a severe mental health problem), and discuss it with your healthcare provider.
This site is intended only for residents of the United States, its territories, and Puerto Rico.
SAPHRIS is a registered trademark of N.V. Organon, a subsidiary of Merck & Co., Inc.
© 2013 MSD Oss B.V., a subsidiary of Merck & Co., Inc.
All rights reserved.